Introduction This Is A Pre Solicitation Non Competitive Notice Of Intent Synopsis To Award A Contract Without Providing For Full Or Open Competition Including Brand Name The National Institute Of Mental Health Nimh Intends To Negotiate On A Sole Source Basis With Mbf Bioscience Inc For Neurolucida System Software Imaging Upgrades And Software Support North American Industry Classification System Naics Code And Set Aside Status The Intended Procurement Is Classified Under Naics Code 511210 Software Publishers With A Size Standard Of 38 5 Million This Acquisition Is Set Aside For Small Businesses Regulatory Authority This Acquisition Is Conducted Under The Authority Of The Federal Acquisition Regulation Far Part 13 Simplified Acquisition Procedures Contracts Awarded Using Far Part 13 Simplified Acquisition Procedures Are Exempt From The Requirements Of Far Part 6 Competition Requirements Far Subpart 13 106 1 B Soliciting From A Single Source Provides That For Purchases Not Exceeding The Simplified Acquisition Threshold Contracting Officers May Solicit From One Source If The Contracting Officer Determines That The Circumstances Of The Contract Action Deem Only One Source Reasonably Available E G Urgency Exclusive Licensing Agreements Brand Name Or Industrial Mobilization The Resultant Contract Will Include All Applicable Provisions And Clauses In Effect Through The Federal Acquisition Circular Fac 2021 05 Dated March 10 2021 Description Of Requirement Purpose And Objectives The Purpose Of The Acquisition Is To Upgrade The Neurolucida Software Currently Used To Process Mouse Brain Images To Produce Full Three Dimensional Reconstructions For Analysis Of Brain Circuits The Upgraded Software Includes Several New Functions That Allow For Analysis Of Neurons That Have Been Specifically Labeled In Research On The Functional Organization Of The Mouse Brain These Upgrades Include A An Enhanced Cell Detector Function Which Uses Newly Developed Image Processing Algorithms To Mark Neurons Labeled By Experimental Procedures Automatically Within The Whole Brain Volume And B Alignment Of Experimental Whole Brain Volumes To A Standard Annotated Reference Atlas Which Allows For Comparison Of Neuron Labeling Across Brains And Quantifies The Numbers Of Neurons In 1000 Brain Structures Biolucida Software Provides An Image Database Integrated With Neurolucida Software That Is Linked To A Server Providing The Ability To Access And Analyze Data Through A Web Based Browser Purchase 4 Neurolucida System Upgrades With 1 Year Software Upgrade And Support Subscription 1 Year Biolucida Software Upgrade And Support Subscription 1 X Biolucida Server Hosted And Managed By Mbf Bioscience 1 X New Nl360 License With 1 Year Software Upgrade And Support Subscription 1 X X Cite Novem Fluorescent Light Source The Salient Product Characteristics Are As Follows Image Acquisition Each Slide With 12 Sections Is Imaged Using Neurolucida Software On Zeiss Microscope With Motor Driven Stage Image Processing The 800 Tiles Are Compiled Into A Single Image Of 12 Brain Sections And Then The Individual Sections Are Identified And Saved As Separate Files Assembly Of Brain Sections Into Fully Reconstructed Brain Image Storage And Access Brain Image Files Are Stored Online Image Files Are Organized Using Tagging Feature Online Access Allows Presentation Of Data And Collaborations The Existing Software Used On The Section On Neuroanatomy Laboratory Of Systems Neuroscience Microscope Imaging Systems Is Manufactured And Distributed Solely By Mbf Bioscience There Are No Other Applications That Can Interface With The Existing Microscope And Stage Drive System And Achieve The Desired End State Salient Characteristics Further Mbf Bioscience Is The Only Contractor That Can Modify The Existing Sof
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