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Bids Are invited for High-Content Automated Confocal Imaging, Screening, And Analysis System - High-Content Confocal Imaging, Screening And Analysis System (2-Camera System) , Objectives , Confocal Capability , Camera , Illumination Source & Filter Sets For Multi-Colour Detection , Complete Environmental Control For Multi-Day Live Cell Imaging , Plate Compatibility , Stage Resolution , Autofocus Capabilities , Certifications: Iso9001/Iso14001/ Iso13485/Iso18001 Certification Required , Image Acquisition And Analysis Software (Minimum 3-User License) , The System Should Be Provided With All Required Dedicated Analysis Softwares. , The Analysis Software Should Come With A Minimum Of At Least 3 Fully Functional (All Modules Available) Server-Based Perpetual License. , Software Should Be Capable Of Label Free Imaging Via Dpc Images, Which Can Be Segmented And Analyzed For Morphology And Texture Changes. The System Should Come With Pre-Trained Deep Neural Networks (Dnns) To Provide Efficient & Reliable Methods For Label Free Imaging, Detection & Segmentation. , The System Software Should Have Ready-To-Go Protocols / Templates Available Such As Proliferation, Autophagy, Migration Etc. It Should Allow The User To Create Movie Exports From Both, The Xyz And 3D View In Various File Formats-Wmy, Avi, Mpeg2 And Png File Series. , The Software Should Enable The User For Visualization Of Cell S Les Such As Spheroids As Xyz View Or As 3D View Along With Interactive 3D View Such As Rotating, Zooming Or Shifting The 3D S Le For Detailed Exploration. The Same System Software Should Enable 3D Segmentation And 3D Analysis Of Cell S Les. Includes 3D Properties Such As Volumes 3D Morphology, 3D Intensity And 3D Position Properties As Well As 3D Textures. , The Analysis Software Should Be Able To Perform Additional Applications: Imaging & Analysis Of Fixed Cell Fluorescence Imaging, Cell Growth, Cell Death, Cell Differentiation, And Migration; Viral Or Bacterial Invasion, Cancer Metastasis, Chemotaxis, Drug Toxicity, Multi Wavelength Cell Sorting, Neurite Outgrowth, Nuclear Translocation Analysis, Protein – Protein Interaction-Based Assays, Fret Based Applications, Stem Cell Studies & Homogeneous Binding Assays. , Background Correction Feature In The Software To Automatically Adjust Image Segmentation To The Local Intensity Ranges And Features Within And Between Cells For Better Quantitation. , The User Should Be Able To Co-Register Images From Bright Field And Fluorescence Modes. , Features For Developing User Defined Modules / Custom Module Editor Should Be Provided In The Software For Any Non-Standard Applications. , System Software Should Include Intelligent Acquisition Modules For Faster Scanning Of Plates By Using Software And Hardware Pieces To Scan And Rescan Images At Low And High Magnification For Specific Areas Of Well/ Cells With Precision. This Acquisition Should Be Possible On The X, Y & Z Axis. , The Acquisition/Analysis Software Should Be Available From The Same Oem. There Should Be No Need For Manual Intervention For Transfer Of Data Files Between Acquisition And Analysis Software. Analysis Software Should Offer Quantitative Information And Display A Graph/Dot Plots/Histogram. , Software Should Have Network Compatibility And Transfer Of Image Files And Experiment Data Files Between An Office Workstation, Nas, And The Imaging Instrument, Further Enabling User Access Within A Multi-User Environment, , Software Should Have The Feature Like Real-Time Image Analysis For Every Application, Enabling Useful On-Line Quality Control Within Screening Programs. , The Software Should Have Integrated Ai Features To Segment Cellular Nuclei In Brightfield Images. , Software Should Offer Supervised Machine Learning Capabilities That Enable The Software To Recognize Different Cell Populations Or Regions. Based On Advanced Machine-Learning Technology, Software Should Then Set Parameters For Optimal Image Segmentation And Cell Classification. , Mention Make/Model, And Year Of Introduction Of The Acquisition And Analysis Software. , Computer Workstation , Suitable Factory Tested Workstation Pc (Compatible With Hcs System) Should Be Provided That Includes Control Computer: Processor: Intel Xeon W5-2465X (16 Cores) - Ram: 128 Gb; Hdd: Raid 10 Configuration, ~22Tb Useable Storage; Graphics Card: Nvidia A4000, 16Gb; Monitor: 34-Inch Flat Screen Or More; Os: Microsoft® Windows® 10 Iot Enterprise 2021 Ltsc, 64Bit, Os Runs On Separate Ssd Drive. Network Interface: 10 Gigabit Ethernet. A 10Gbit Port Is Available To Connect To The Customer Network. Microsoft Sql Server Standard 2019 Incl. 5 Client Access Licenses (Cal). Keyboard And Mouse With All Wires And Connectors To Make The System Fully-Functional. , The Vendor Shall Ensure That All Drivers, Firmware, And Associated Software Components Of The Computer Workstation Are Updated And Maintained, As Required, To Ensure Seamless Compatibility With The Perpetually Licensed Software Throughout The Operational Life (End-Of-Life) Of The Hcs System. , Mention Make, Model, And Year Of Introduction Of The Computer Workstation Systems. , High-End Workstation For Image Analysis And Data Processing -Two (2) , Processor (Cpu): Dual Latest-Generation Intel Xeon Scalable Processors (Intel Xeon Platinum Series Or Higher), Minimum 60 Cores Per Cpu; (Preferred: Intel Xeon Platinum 8490H Or Higher.) , Motherboard/Chipset: Oem Workstation/Server Motherboard Supporting Dual Intel Xeon Scalable Processors, Pcie Gen5 Architecture, Ecc Memory, Multiple Pcie Gen5 X16 Slots, And Future Cpu, Gpu, Memory, And Storage Expansion. , Memory (Ram): Minimum 512 Gb Ddr5 Ecc Registered Ram, Expandable Up To 4 Tb. , Graphics Processing Unit (Gpu): Preferred: 1 × Nvidia Rtx Pro 6000 Blackwell Gpu. Alternative: Support For 2 × Nvidia Geforce Rtx 5090 (Or Equivalent Latest High-End Gpu). , Operating System Drive: 2 × 2 Tb Nvme Gen4/Gen5 Ssd Configured In Raid 1 For Operating System And Applications. , Data Storage: 4 × 8 Tb Enterprise-Grade Hdd Configured In Raid 10 For Local Storage And Cache Workloads. , Raid Controller: Hardware: Raid Controller Supporting Raid 0, 1, 5, 6, 10, 50 (Minimum), With Raid 1 And Raid 10 Configuration As Specified. , Network Interface: Dual-Port 100 Gbe Sfp28 Ethernet Adapter And Dual-Port 10 Gbe Rj45 Ethernet Adapter For High-Speed Nas Connectivity. , Expansion Slots: Pcie Gen5 X16 Expansion Slots With Provision For Additional Gpus, Storage Controllers, And Network Adapters. , Cooling: Oem Enterprise-Grade Thermal Solution Suitable For Dual Cpus And High-End Gpu(S). , Ports & Connectivity: Usb Type-C (Usb 3.2 Gen2x2 Or Higher) Mandatory, Usb 3.X Ports, Video Outputs, And Standard Enterprise I/O Ports. , Display: 2 × 34-Inch Ultrawide Qhd (3440 × 1440) Ips Professional Monitors With Usb-C, Display Port, Hdmi, Minimum 99% Srgb Color Gamut, Height-Adjustable Stand. (Preferred: 2 × 43-Inch 4K Uhd (3840 × 2160) Professional-Grade Ips Monitors With Factory Color Calibration, Hdr Support, Anti-Glare Coating, Usb-C With Power Delivery, Displayport, Hdmi, And Vesa Mount Compatibility.) , Keyboard & Mouse: Wireless Keyboard And Wireless Optical Mouse. , Operating System: Microsoft Windows 11 Enterprise Or Professional (64-Bit), Pre-Installed And Licensed. , Workload Suitability: Optimized For Ai/Ml, Microscopy Imaging, High-Performance Computing (Hpc), And Advanced Visualization Workloads. , Expandability: Provision For Future Cpu, Gpu, Memory, Storage, And Pcie Expansion. , Installation & Commissioning: Supply, Installation, Testing, Commissioning, And Successful Handover Of The Complete System With All Required Accessories And Cables. , Mention Make, Model, And Year Of Introduction Of The Workstation System Provided. , Data Storage , Network Attached Storage (Nas) Solution With At Least 1 Pb Usable Storage Capacity With 50% Redundancy, Expandable Up To 4 Pb. , The Storage System Shall Be Equipped With Enterprise-Grade Nl-Sas Drives And 4–8 Enterprise-Grade 8 Tb Nvme Ssds For Metadata And Cache Acceleration. , The Solution Shall Support Raid 0, 1, 5, 6, 10, And Hybrid Raid Configurations. , The Storage System Shall Support A Minimum Of Two Redundant Storage Controllers, Each Equipped With At Least 512 Gb Ecc Ram. , The Storage System Shall Provide A Minimum Of 4 × 25 Gbe Sfp28 Ports And Support 100 Gbe Connectivity For High-Speed Data Transfer. , The Solution Shall Support A Minimum Aggregate Throughput Of 10 Gb/S, With Multipathing, Link Aggregation, Non-Disruptive Failover, And Fully Redundant Hot-Swappable Components.
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