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1.

ADVANCED SUBSTRATE TECHNOLOGIES AS

Mushroom and biogas production in a circular economy

  • 5 Million
  • Denmark
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Mushroom and biogas production in a circular economy
Company Name ADVANCED SUBSTRATE TECHNOLOGIES AS
Country Denmark , Western Europe
Project Value 5 Million
Project Detail

The problems: Biogas is important for the European renewable energy transition as it turns waste streams such as manure and sewage into biogas, and provides CO2-neutral energy. But the efficiency is low because the methane producing bacteria in the biogas digester have trouble accessing the energy locked in fibrous materials such as cellulose and lignin. This fraction passes through the biogas plant unused and is incinerated or spread on agricultural land. At the same time, mushroom producers must buy substrate to grow mushrooms and pay to discard it after use. The solution: The AST technology creates a resource cycle between biogas production and mushroom production, reducing costs of mushroom production by up to 50% and utilizing also the fibrous fraction in biogas plants. The innovation is a technology where the fibrous fraction from biogas is used for growing mushrooms, and then returned to the biogas plant, offering improved economy as well as significant environmental benefits to both the mushroom and biogas industry. The project: The AST concept has already been proven in pilot scale, and the next step is a full scale demonstration plant. In this project two AST plants are scaled up and integrated with mushroom production facilities and a biogas plant, respectively. It is essential for the market introduction and thus the commercial success to demonstrate such commercial operation for customers to invest in such plants. Impact: The project will increase the competitiveness of the European mushroom industry currently under strong pressure from China, as well as the biogas industry, suffering from high operational costs. The market: Biogas plants are rapidly being established to support the renewable energy transition with more than 15,000 plants currently in operation in Europe. The European mushroom industry uses about 3 m tons of substrate annually and grows with 10%. The market for the innovation is large, has a growing trend and strong drivers.

Sector Administration & Marketing

Contact Details

Company Name ADVANCED SUBSTRATE TECHNOLOGIES AS
Address Niels Pedersens Alle 2 8830 Tjele
Web Site https://cordis.europa.eu/project/rcn/212144/factsheet/en

2.

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS

Correlated frontiers of many-body quantum mathematics and condensed matter physics

  • 1 Million
  • France
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Correlated frontiers of many-body quantum mathematics and condensed matter physics
Company Name CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
Country France , Western Europe
Project Value 1 Million
Project Detail

One of the main challenges in condensed matter physics is to understand strongly correlated quantum systems. Our purpose is to approach this issue from the point of view of rigorous mathematical analysis. The goals are twofold: develop a mathematical framework applicable to physically relevant scenarii, take inspiration from the physics to introduce new topics in mathematics. The scope of the proposal thus goes from physically oriented questions (theoretical description and modelization of physical systems) to analytical ones (rigorous derivation and analysis of reduced models) in several cases where strong correlations play the key role. In a first part, we aim at developing mathematical methods of general applicability to go beyond mean-field theory in different contexts. Our long-term goal is to forge new tools to attack important open problems in the field. Particular emphasis will be put on the structural properties of large quantum states as a general tool. A second part is concerned with so-called fractional quantum Hall states, host of the fractional quantum Hall effect. Despite the appealing structure of their built-in correlations, their mathematical study is in its infancy. They however constitute an excellent testing ground to develop ideas of possible wider applicability. In particular, we introduce and study a new class of many-body variational problems. In the third part we discuss so-called anyons, exotic quasi-particles thought to emerge as excitations of highly-correlated quantum systems. Their modelization gives rise to rather unusual, strongly interacting, many-body Hamiltonians with a topological content. Mathematical analysis will help us shed light on those, clarifying the characteristic properties that could ultimately be experimentally tested.

Sector Administration & Marketing

Contact Details

Company Name CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
Address Rue Michel Ange 3 75794 Paris
Web Site https://cordis.europa.eu/project/rcn/212102/factsheet/en

3.

SINERGISE LABORATORIJ ZA GEOGRAFSKE INFORMACIJSKE SISTEME DOO

Perceptive Sentinel – BIG DATA knowledge extraction and re-creation platform

  • 2 Million
  • Slovenia
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Perceptive Sentinel – BIG DATA knowledge extraction and re-creation platform
Company Name SINERGISE LABORATORIJ ZA GEOGRAFSKE INFORMACIJSKE SISTEME DOO
Country Slovenia , Southern Europe
Project Value 2 Million
Project Detail

PerceptiveSentinel project will deliver PerceptiveSentinel platform - an INTERMEDIATE EO service that will through seamless access to highly pre-processed DATA provide: - MODELLING and PUBLISHING capabilities for - DESIGN, EXPOSURE and EXPLOITATION of EO-processing chains for - FORECASTING, MONITORING and HISTORICAL ANALYSIS in different domain fields, based on - MULTI-TEMPORAL and MULTI-SPECTRAL EO-Data and Non-EO Data MODELLING. PerceptiveSentinel platform will combine BIG-DATA SOURCES, (2) both spatial and non-spatial, (2) whether remote sensed, observed in-situ or derived (3) whether public, private or proprietary—onto a single system. The data will be transformed into action by applying STREAMING MACHINE LEARNING to UNLOCK its value. Platform’s capabilities will significantly shorten development cycles, enabling rapid development of EO services, opening new opportunities for large-scale exploitation of data and provide the means for new EO “downstream players” to smoothly enter the market without the investment into their own storage and processing capabilities. Commercialisation approach will be based on (1) FREE and OPEN access to services and data, (2) OPEN-VALUE-CHAIN approach, (3) LOW COST of services and on (4) DELIVERING VALUE TO END USERS. It is our intention that PerceptiveSentinel platform becomes FIRST value and benefit sharing EO platform in the world. We intent to expose an alternative business model building on COOPERATIVE VALUE CREATION and capture, including all aspects of EO value chain from data providing, product/service development, publishing and consuming. We believe in synergetic effects of cooperation, using PerceptiveSentinel platform to establish alliances with external partners, taking an open approach to participation and building joint commercial success on the delivery of new added value.

Sector Administration & Marketing

Contact Details

Company Name SINERGISE LABORATORIJ ZA GEOGRAFSKE INFORMACIJSKE SISTEME DOO
Address Cvetkova Ulica 29 1000 Ljubljana
Web Site https://cordis.europa.eu/project/rcn/212428/factsheet/en

4.

ENGINEERING - INGEGNERIA INFORMATICA SPA

Enabling Smart Energy as a Service via 5G Mobile Network advances (NRG-5)

  • 7 Million
  • Italy
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Enabling Smart Energy as a Service via 5G Mobile Network advances (NRG-5)
Company Name ENGINEERING - INGEGNERIA INFORMATICA SPA
Country Italy , Western Europe
Project Value 7 Million
Project Detail

Despite a number of software frameworks and reference architectures have made available for 5G enabling technologies, there is a clear gap to bridge towards 5G seamless application with a number of “vertical” sectors. Energy vertical represents undoubtedly one of the most significant “test cases” for 5G enabling technologies, due to the need of addressing a huge range of very diverse requirements to deal with across a variety of applications (stringent capacity for smart metering/AMI versus latency for supervisory control and fault localization).However, to effectively support energy utilities along their transition towards more decentralized renewable-oriented systems, several open issues still remain as to 5G networks management automation, security, resilience, scalability and portability. To face these issues, NRG-5 will research and develop a novel 5G PPP-compliant software framework specifically tailored to the energy domain, which combines i) trusted, scalable and lock-in free plug ‘n’ play support for a variety of constrained devices; ii) 5G devices’ abstractions to demonstrate mMTC, uMTC and xMBB communications coupled with partially distributed, trusted, end-to-end security and MCM to enable secure, scalable and energy efficient communications; iii) extended Mobile Edge Computing (xMEC) micro-clouds to reduce backhaul load, increase the overall network capacity and reduce delays, while facilitating the deployment of generic MTC-related NFVs and utility-centric VNFs; iv) an extended 5G ETSI-MANO predictive analytics framework to support automated, dynamic, elastic VNF reconfiguration. Extensive lab based validation will be complemented with real life demonstrations in two pilot sites (Italy, France) where proof-of-concept implementations for 5G-enabled electricity and gas distribution network optimized management will be offered, while offering support to 5G PPP phase III projects via demonstrating high replication potential towards other verticals.

Sector Administration & Marketing

Contact Details

Company Name ENGINEERING - INGEGNERIA INFORMATICA SPA
Address Piazzale DellAgricoltura 24 00144 Roma
Web Site https://cordis.europa.eu/project/rcn/211088/factsheet/en

5.

UNIVERSITA DEGLI STUDI DI PAVIA

Genetically engineered human pluripotent stem cells, functionalized silk-fibroin platforms and bio-inks: a novel solution for large-scale ex-vivo platelet production, transfusion and drug research

  • 3 Million
  • Italy
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Genetically engineered human pluripotent stem cells, functionalized silk-fibroin platforms and bio-inks: a novel solution for large-scale ex-vivo platelet production, transfusion and drug research
Company Name UNIVERSITA DEGLI STUDI DI PAVIA
Country Italy , Western Europe
Project Value 3 Million
Project Detail

"The demand for human platelets (plts) for medical research and clinical applications is massive. The primary goal of SilkFUSION is to engineer groundbreaking 3D nanotechnologies for large-scale production of blood plts for human transfusion from human pluripotent stem cells (hPSCs). Our hypothesis is that plt production ex-vivo can be optimized by providing megakaryocytes (Mks) with the correct physical and biochemical environment. To prove this, we will develop a unique technological platform by engineering non-thrombogenic silk-fibroin biomaterial with proteins, that were proven to promote a 55-fold gain in plt production, to create a three-dimensional ex-vivo bone marrow model that will enhance plt release from Mks derived from hPSCs. Our platform will include (i) novel applications to study pathogenetic mechanisms in patients with inherited platelet production disorders using genetically modified hPSCs; (ii) screening technology for predicting therapeutic efficacy of drugs for thrombocytopenic patients. The development of this technology will exploit an extremely innovative approach using silk-fibroin as a bio-ink for 3D printing a ""live chip"" containing viable Mks for reproducible drug testing. Our long-term vision is to foster the production of plts in-vitro for clinical transfusions in humans at a scale and cost that will address current supply challenges regarding (i) immunologically matched products to alloimmunised patients; (ii) “supercharged” platelets with recombinant FVIIa generating plts specifically suited for patients with acute haemorrhage resulting from trauma, surgery and wounded in conflict zones. The successful development and distribution of the SilkFUSION platforms will also offer researchers and clinicians specialized precision instruments and bio-ink kits for determining the safety and efficacy of drugs, reducing costs of ineffective therapies while promoting affordable functional strategies for the development of novel molecules."

Sector Administration & Marketing

Contact Details

Company Name UNIVERSITA DEGLI STUDI DI PAVIA
Address Strada Nuova 65 27100 Pavia
Web Site https://cordis.europa.eu/project/rcn/212353/factsheet/en

6.

ARISTOTELIO PANEPISTIMIO THESSALONIKIS

EXPLORING THE NEUROLOGICAL EXPOSOME

  • 3 Million
  • Greece
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EXPLORING THE NEUROLOGICAL EXPOSOME
Company Name ARISTOTELIO PANEPISTIMIO THESSALONIKIS
Country Greece , Western Europe
Project Value 3 Million
Project Detail

The main objective of NEUROSOME is to develop an integrative biology-based framework starting from human biomonitoring data to unravel causal associations among the genetic predisposition, cumulative exposure to multiple environmental chemicals and neurological disorders. The project brings together beyond- the-state-of-the-art advances in human biomonitoring and systems biology, exposure monitoring and toxicological testing technologies and advanced tools for computational analyses of the exposure-to-health effect continuum following an exposome paradigm. The NEUROSOME methodology will be applied in population studies across different exposure settings to neurotoxicants (metals and persistent organics) in Europe. This will improve scientific knowledge on cause and-effect relations between environmental stressors and neurodevelopmental disorders taking into account exposure and health effect modification due to intrinsic (e.g. genetic susceptibility) and extrinsic (e.g. diet and socioeconomic status) factors. New standards for human biomonitoring data interpretation in conjunction with environmental and exposure information will be developed for ready use in chemical mixture risk assessment. The training goal is to produce a new generation of exposome researchers, trained in academia, applied research and industry, with transdisciplinary skills (environmental end exposure modelling, human biomonitoring, -omics technologies, high dimensional bioinformatics and environmental epidemiology,) and understanding of fundamental science and its direct application to environmental health challenges. To this aim NEUROSOME will focus on the provision of trans-disciplinary research training to young researchers through a combination of network-wide training programs and individual personalised training-through-research projects to deliver to the EU and the world a new cohort of researchers trained in cutting edge transdisciplinary environmental health sciences

Sector Administration & Marketing

Contact Details

Company Name ARISTOTELIO PANEPISTIMIO THESSALONIKIS
Address Kedea Building, Tritis Septemvriou, Aristotle Univ Campus 54636 Thessaloniki
Web Site https://cordis.europa.eu/project/rcn/211910/factsheet/en

7.

UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN

The Gendered Politics of Emotion in Austerity Ireland

  • 187,866
  • Ireland
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The Gendered Politics of Emotion in Austerity Ireland
Company Name UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN
Country Ireland , Northern Europe
Project Value 187,866
Project Detail

This research project surveys and theorises the politics of shame in the contemporary Irish context. It identifies the deployment and manipulation of emotions in public discourses, particularly with regard to historically marginalised groups, since the onset of the economic crisis, and teases out the gendered and classed operation of the politics of shame. The project establishes the role shame plays in the contemporary political setting post-2008 with the introduction of austerity as a policy-response to the economic crisis. Building on theoretical work highlighting the increased shame-proneness of traditionally disadvantaged groups, the project examines the linkage between gender and shame. Although shame has been understood to be entangled with patriarchal norms concerning women’s bodies and sexuality it has, so far, not been theorised with regard to gender and material disadvantage and poverty. There is some empirical evidence that shame, does, in fact, manifest itself in impoverished populations, and that this may be amplified or at least complicated by gender. The project forms the first political theoretical treatment of the economic crisis and the policy-response to same, and focuses, uniquely, on gender and class. It will does so, again uniquely, through a framing in terms of affect and the politics of emotion. The project seeks to capture just how those experiencing austerity most immediately, conceptualise their disproportionate disadvantaging, and whether they themselves engage a politics of shame. The training and career development provisions of the project aim to enhance the researchers profile as a specialist in gender, who is equally adept at engaging social science and humanities research methods, and facilitate a deeper probing of a complex empirical context as it relates to gender, shame, and economic disadvantage.

Sector Administration & Marketing

Contact Details

Company Name UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN
Address Belfield 4 Dublin
Web Site https://cordis.europa.eu/project/rcn/212276/factsheet/en

8.

KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW

A single-cell genomics approach integrating gene expression, lineage, and physical interactions

  • 3 Million
  • Netherlands The
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A single-cell genomics approach integrating gene expression, lineage, and physical interactions
Company Name KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW
Country Netherlands The , Western Europe
Project Value 3 Million
Project Detail

From populations of unicellular organisms to complex tissues, cell-to-cell variability in phenotypic traits seems to be universal. To study this heterogeneity and its biological consequences, researchers have used advanced microscopy-based approaches that provide exquisite spatial and temporal resolution, but these methods are typically limited to measuring a few properties in parallel. On the other hand, next generation sequencing technologies allow for massively parallel genome-wide approaches but have, until recently, relied on studying population averages obtained from pooling thousands to millions of cells, precluding genome-wide analysis of cell-to-cell variability. Very excitingly, in the last few years there has been a revolution in single-cell sequencing technologies allowing genome-wide quantification of mRNA and genomic DNA in thousands of individual cells leading to the convergence of genomics and single-cell biology. However, during this convergence the spatial and temporal information, easily accessed by microscopy-based approaches, is often lost in a single-cell sequencing experiment. The overarching goal of this proposal is to develop single-cell sequencing technology that retains important aspects of the spatial-temporal information. In particular I will focus on integrating single-cell transcriptome and epigenome measurements with the physical cell-to-cell interaction network (spatial information) and lineage information (temporal information). These tools will be utilized to (i) explore the division symmetry of intestinal stem cells in vivo; (ii) to reconstruct the cell lineage history during zebrafish regeneration; and (iii) to determine lineage relations and the physical cell-to-cell interaction network of progenitor cells in the murine bone marrow.

Sector Administration & Marketing

Contact Details

Company Name KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW
Address Kloveniersburgwal 29 Het Trippenhuis 1011 Jv Amsterdam
Web Site https://cordis.europa.eu/project/rcn/212260/factsheet/en

9.

Sign time GmbH

SiMAX - The Sign Language Avatar

  • 2 Million
  • Austria
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SiMAX - The Sign Language Avatar
Company Name Sign time GmbH
Country Austria , Western Europe
Project Value 2 Million
Project Detail

The Austrian SME signtime has combined its expertise in sign language translation and ICT tool development delivering SiMAX, an innovative translation “machine” easy to use: A human translator only needs to adjust translations suggested by smart algorithms on a “learning” database. The result: A video showing an avatar signing. The process is flexible for future adaptations, less time and cost consuming than classical translation videos produced in a studio with human translators signing. Compared to other mostly academic sign language translation approaches SiMAX is closest to market and the only one reaching a feasible quality of facial expressions essential for understanding due to grammatical meanings in sign languages. Business opportunities are enormous associated with making information accessible to the deaf community: any digital content (for web publishing or other purposes), TV, film. Accessibility regulations favour market growth and demand. During the project SiMAX will be adapted to TRL 9 working as cloud solution and fine-tuned for mass-production. Pilot translations of citizen and consumer information (for public authorities and companies) will be carried out in Germany, UK, France and Poland together with translators, another important customer/partner group. We will further raise maximum attention for SiMAX translations in the deaf community and will inform key stakeholders and potential customers about SiMAX and its added values for them. A commercialization strategy for market entry across the EU will be prepared and evaluated within the project. The project fits with the requirements of this SME call, adding a completely new, market changing solution. SiMAX provides significant growth options to our company and perfectly fits with our overall strategy. Societally, it can essentially contribute to increase accessibility to information society for the deaf community thus contributing to inclusion and social cohesion in the EU.

Sector Administration & Marketing

Contact Details

Company Name Sign time GmbH
Address Schottenring 33 1010 Wien
Web Site https://cordis.europa.eu/project/rcn/211756/factsheet/en

10.

KOBENHAVNS UNIVERSITET

Rapid Biomechanics Simulation for Personalized Clinical Design

  • 4 Million
  • Denmark
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Rapid Biomechanics Simulation for Personalized Clinical Design
Company Name KOBENHAVNS UNIVERSITET
Country Denmark , Western Europe
Project Value 4 Million
Project Detail

Clinical experts make design decisions on treatments, interventions, or on devices. ICT empowers them with patient-specific simulation models that enable better-informed design decisions. But patient-specific computational medicine is currently cumbersome, slow, and unintuitive; it relies on complex processing by technical experts, and it is hence far from reaching its full potential on clinical design, and scarcely used. RAINBOW envisions next-generation biomechanics simulation and optimization tools for personalized clinical design that are rapidly setup for a particular patient, have a fast learning curve, are easy-to-use by clinical experts, and do not require intervention by a technical team. Research objectives entail automated processing of patient data; automated setup of representations and parameters, capability to manage variance across patients; robust and accurate simulation as a latent part of design tools; and fast optimization methods that allow intuitive exploration of the design space. Novel computational methods will be created to reach the objective of rapid biomechanics simulation. RAINBOW will apply research solutions for diagnosis, prognosis, monitoring, surgical training, planning, guidance, design of prosthetics, implants, and medical devices, and will address health conditions such as osteoarthritis, scoliosis, hearing impairment, cardiovascular diseases, obesity etc. RAINBOW has 5 excellent academic participants: UCPH (medical imagine, machine learning), URJC (data-driven modeling), UL (computational mechanics), CARDIFF (model reduction), AAU and one hospital HH (bone modeling) and 8 industries 3Shape (prosthesis), Kitware (imaging), Insimo (surgical simulation), GMV (eHealth), Simpleware (CAD/CAE), inuTech (numerics), Anatascope (Patient specific modeling) and Next-Limit (CFD). This combined expertise will ensure diverse impact and training of highly qualified individuals.

Sector Administration & Marketing

Contact Details

Company Name KOBENHAVNS UNIVERSITET
Address Norregade 10 1165 Kobenhavn
Web Site https://cordis.europa.eu/project/rcn/211738/factsheet/en

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