| Project Detail |
Development of synthetic glycans for the treatment of norovirus infection
Glycans are carbohydrates ubiquitously present on cell surfaces, playing key roles in many biological processes, including mediation of virus attachment and entry. Human noroviruses (NoVs) cause gastroenteritis and foodborne illnesses with severe complications in immunocompromised individuals, the elderly, and young children. Currently, there is no therapy available to prevent or treat NoV infections. Funded by the Marie Sklodowska-Curie Actions programme, the GlycoNoVi project goal is to train 9 researchers and study the NoV interactions with glycans and mechanisms underlying the virus’ attachment to specific glycans to infect host cells. The objective is to investigate the exciting possibility of developing synthetic glycans for the prevention and treatment of NoV infection. |
