| Project Detail |
Antimicrobial resistance (AMR) due to multidrug-resistant Gram-negative bacteria are an increasingly serious healthcare threat, exacerbated by major economic issues underlying the development of new antibacterial drugs. The effectiveness of ß-lactam antibiotics, the most important class of antibacterial agents, is impaired by the production of ß-lactamase enzymes by drug-resistant bacteria.
We are developing a combination of a well-known antibiotic (meropenem) and ANT3310, our proprietary, best-in-class serine-ß-lactamase inhibitor, intended for the treatment of hospital-acquired infections caused by drug-resistant pathogens. Our treatment has been pre-clinically proven to be efficacious against all three pathogens deemed a critical priority by the World Health Organization (WHO).
We will conduct three clinical trials and next out-license ANT3310 to a pharmaceutical partner. We expect market approval by 2029 and that ANT3310 will generate over €10bn in sales within 13 years. |
