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1.

ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS

MyPal: Fostering Palliative Care of Adults and Children with Cancer through Advanced Patient Reported Outcome Systems

  • 4 Million
  • Greece
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MyPal: Fostering Palliative Care of Adults and Children with Cancer through Advanced Patient Reported Outcome Systems
Company Name ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS
Funded By 38
Country Greece , Western Europe
Project Value 4 Million
Project Detail

MyPal aims to foster early palliative care for cancer patients by leveraging patient reported outcome (PRO) systems through their adaptation to the personal needs of the cancer patient and his/her caregiver(s). Through this intervention, MyPal aspires to empower cancer patients (and their family members) in capturing more accurately their conditions, communicate them with a seamless and effective way to their healthcare providers and, ultimately, foster the time for action through the rapid identification of important deviations in the patient’s state and QoL. Providing this information in a timely and comprehensive manner throughout the disease course will reinforce the potential for applying a patient-centred and integrated palliative care approach for cancer with the participation of all relevant healthcare providers (i.e. oncologists, specialized physicians, psychologists, nurses), which is necessary to cope with the specific disease. In order to accomplish its mission, MyPal will exploit technological advances on digital health to support patients, family members and healthcare providers in gaining value through this systematic and comprehensive PRO-based intervention. Overall, the foreseen advancement through MyPal reflects a paradigm shift from passive patient reporting based on conventional PRO approaches to active patient engagement and a closed-loop approach (bridging the gap between patient reporting and effective actions by healthcare providers to meet the varying patient needs) for coping with palliative care challenges in cancer. MyPal will demonstrate and validate the proposed intervention in two clinical studies, an RCT for adults with hematologic cancers and an observational study for children suffering from solid tumors and hematologic malignancies, hence targeting different age groups and cancer types. The clinical studies will be conducted in diverse healthcare settings in 6 clinical sites from 5 European countries.

Sector Administration & Marketing

Contact Details

Company Name ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS
Web Site https://cordis.europa.eu/project/rcn/220959/factsheet/en

2.

Port of Long Beach

Gerald Desmond Bridge Replacement Project

  • 650 Million
  • United States
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Gerald Desmond Bridge Replacement Project
Company Name Port of Long Beach
Funded By 107
Country United States , Northern America
Project Value 650 Million
Project Detail

Project Type: Highways & Bridges | Procurement Type: Design-Build State: California | Status: Ongoing The purpose of the project is to replace the aging bridge with a modern structure that conforms to all updated seismic codes while providing for a 100-year design life. In addition, the new bridge will provide for a minimum 200-foot clearance above the Port channel to accommodate the largest cargo ships, while increasing the vehicular capacity of the I-710 freeway. The Cable-Stayed Bridge The centerpiece of the project is the cable-stayed bridge that will stretch 1,000 feet between the two 500-foot tall pylons, with 500-foot long high approaches at each end. The pylon towers will be unique octagonal single tower structures that transform to a diamond shape at the top. Approaches and Interchanges The approaches to the new signature structure are designed as a single unit with the main span. The approach bridges are comprised of two independent concrete box girders with cantilever decks. Most of the approaches are constructed using the Moveable Scaffold System (MSS) method. The project also includes new interchanges between the I-710 freeway and Ocean Boulevard, Pico Avenue, and SR-47. A bike path will also be provided across the new bridge.

Sector Administration & Marketing

Contact Details

Company Name Port of Long Beach
Address 4801 Airport Plaza Drive Long Beach, CA 90815 or P.O. Box 570 Long Beach, CA 90801 (562) 283-7000 24 hrs. (562) 283-7820
Web Site https://www.laneconstruct.com/portfolio/gerald-desmond-bridge

3.

ALFRED-WEGENER-INSTITUT HELMHOLTZ-ZENTRUM FUR POLAR- UND MEERESFORSCHUNG

Stratospheric and upper tropospheric processes for better climate predictions

  • 11 Million
  • Germany
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Stratospheric and upper tropospheric processes for better climate predictions
Company Name ALFRED-WEGENER-INSTITUT HELMHOLTZ-ZENTRUM FUR POLAR- UND MEERESFORSCHUNG
Funded By European Union
Country Germany , Western Europe
Project Value 11 Million
Project Detail

StratoClim will produce more reliable projections of climate change and stratospheric ozone by a better understanding and improved representation of key processes in the Upper Troposphere and Stratosphere (UTS). This will be achieved by an integrated approach bridging observations from dedicated field activities, process modelling on all scales, and global modelling with a suite of chemistry climate models (CCMs) and Earth system models (ESMs). At present, complex interactions and feedbacks are inadequately represented in global models with respect to natural and anthropogenic emissions of greenhouse gases, aerosol precursors and other important trace gases, the atmospheric dynamics affecting transport into and through the UTS, and chemical and microphysical processes governing the chemistry and the radiative properties of the UTS. StratoClim will (a) improve the understanding of the microphysical, chemical and dynamical processes that determine the composition of the UTS, such as the formation, loss and redistribution of aerosol, ozone and water vapour, and how these processes will be affected by climate change; (b) implement these processes and fully include the interactive feedback from UTS ozone and aerosol on surface climate in CCMs and ESMs. Through StratoClim new measurements will be obtained in key regions: (1) in a tropical campaign with a high altitude research aircraft carrying an innovative and comprehensive payload, (2) by a new tropical station for unprecedented ground and sonde measurements, and (3) through newly developed satellite data products. The improved climate models will be used to make more robust and accurate predictions of surface climate and stratospheric ozone, both with a view to the protection of life on Earth. Socioeconomic implications will be assessed and policy relevant information will be communicated to policy makers and the public through a dedicated office for communication, stakeholder contact and international co-operation.

Sector Science & Research

Contact Details

Company Name ALFRED-WEGENER-INSTITUT HELMHOLTZ-ZENTRUM FUR POLAR- UND MEERESFORSCHUNG
Address AM HANDELSHAFEN 12 27570 BREMERHAVEN Germany
Web Site https://cordis.europa.eu/project/rcn/111345_en.html

4.

UNIVERSITE DE LAUSANNE

Bridging MICroevolution and MACroevolution in sticklebacks

  • 251,332
  • Switzerland
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Bridging MICroevolution and MACroevolution in sticklebacks
Company Name UNIVERSITE DE LAUSANNE
Funded By European Union
Country Switzerland , Western Europe
Project Value 251,332
Project Detail

How is biodiversity generated? What are the main factors affecting the emergence of biodiversity and its evolution? To answer these questions, since more than one century, evolutionary biologists have been studying life with two separated approaches: either population biologists tend to study evolution of individuals and divergence of populations below the species level (microevolution), or paleontologists and phylogeneticists are studying the diversification and the extinction of species at a much coarser scale (macroevolution). Only extremely rare studies have permitted to make the link between micro and macroevolution and an integrative approach bridging the two scales is currently lacking. In this project, I propose to study the factors affecting the diversification process (speciation and extinction) and phenotypic evolution (morphology and ecological niche) at the two different evolutionary scales using two datasets: (i) a completely new dataset of 300 three- spined stickleback genomes distributed in more than 100 populations in North America and (ii) a much broader dataset encompassing genomes for each species of the Gasterosteidae family (including sticklebacks) permitting to reconstruct the relationships between species. This project will be composed by two distinct phases: the first phase consists in generating genomic sequences with Next Generation Sequencing and running microevolution analyses with D. Schluter in University of British Colombia (Vancouver, Canada); and the second phase will permit to build a new theoretical integrative framework permitting to explain the bridges between micro and macroevolution with N. Salamin in University of Lausanne (Switzerland). My aim is to strongly stimulate the interactions between the different communities of researchers in evolution, and to promote evolutionary research to a broader audience through public talks in museums and primary/secondary schools.

Sector Services

Contact Details

Company Name UNIVERSITE DE LAUSANNE
Address Quartier Unil-Centre Bâtiment Unicentre 1015 LAUSANNE Switzerland
Web Site https://cordis.europa.eu/project/rcn/214087_en.html

5.

Caltrans – Port of Long Beach

Gerald Desmond Bridge

  • 540 Million
  • United States
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Gerald Desmond Bridge
Company Name Caltrans – Port of Long Beach
Funded By -
Country United States , Northern America
Project Value 540 Million
Project Detail

The project consists of the replacement of Gerald Desmond Bridge, constructed in 1968 over the Back Channel of the Port of Long Beach. It is being replaced for reasons of seismic risk, because of heavy-traffic growth over the coming years and the need for greater vertical clearances for current container ships. The project includes approach structures on Ocean Boulevard, the reconfiguration and improvement of two intersections, the construction of a bicycle lane along the length of the route and the diversion of affected services. The main structure is resolved by means of a cable-stayed bridge with a 305-metre long principal span at 61 metres over the Back Channel and two 152-metre long end spans. The project was designed with two 155-metre maximum height, single-shaft towers, 90 metres above the deck. Each mast has two planes of ten cables from its head to the deck edge. Each tower is cemented over twelve 2.4 metre diameter piles connected by variable octagonal capping between 3 and 4.90 metres. The deck is 47 metres wide and consists of longitudinal metal beams at the ends and transversal metal beams spaced at five metres. Prefabricated, full-edge slabs are positioned on this metal structure with the joints between them being concreted onsite. The approach bridges to the stayed section are 900 metres long on the west side and 1,155 metres long on the east side. These are made up of spans between 57 and 69 metres, with caisson sections, mostly executed onsite with a movable scaffolding system (MSS). To the west of the bridge, an underpass is being executed adjoining the existing one at the intersection between Ocean Boulevard and the SR-47. To the east, the intersection joining Ocean Boulevard to the 710 highway, Pico Avenue and the E and D quays will be remodelled. Remarkable aspects Worldwide first-class successful bid. It connects the heart of the Terminal Island port complex to the Port of Long Beach and is the passing zone towards the city centre and other nearby Californian localities. The construction of the Gerald Desmond Bridge is providing employment to 3,000 people per year and involves a positive impact on the Southern California economy.

Sector Bridges and Tunnels

Contact Details

Company Name Caltrans – Port of Long Beach
Web Site http://www.ciudadfcc.com/en/-/puente-gerald-desmond

6.

UNIVERSITE DE LAUSANNE

Bridging MICroevolution and MACroevolution in sticklebacks

  • 251,332
  • Switzerland
view notice less notice
Bridging MICroevolution and MACroevolution in sticklebacks
Company Name UNIVERSITE DE LAUSANNE
Funded By European union
Country Switzerland , Western Europe
Project Value 251,332
Project Detail

How is biodiversity generated? What are the main factors affecting the emergence of biodiversity and its evolution? To answer these questions, since more than one century, evolutionary biologists have been studying life with two separated approaches: either population biologists tend to study evolution of individuals and divergence of populations below the species level (microevolution), or paleontologists and phylogeneticists are studying the diversification and the extinction of species at a much coarser scale (macroevolution). Only extremely rare studies have permitted to make the link between micro and macroevolution and an integrative approach bridging the two scales is currently lacking. In this project, I propose to study the factors affecting the diversification process (speciation and extinction) and phenotypic evolution (morphology and ecological niche) at the two different evolutionary scales using two datasets: (i) a completely new dataset of 300 three- spined stickleback genomes distributed in more than 100 populations in North America and (ii) a much broader dataset encompassing genomes for each species of the Gasterosteidae family (including sticklebacks) permitting to reconstruct the relationships between species. This project will be composed by two distinct phases: the first phase consists in generating genomic sequences with Next Generation Sequencing and running microevolution analyses with D. Schluter in University of British Colombia (Vancouver, Canada); and the second phase will permit to build a new theoretical integrative framework permitting to explain the bridges between micro and macroevolution with N. Salamin in University of Lausanne (Switzerland). My aim is to strongly stimulate the interactions between the different communities of researchers in evolution, and to promote evolutionary research to a broader audience through public talks in museums and primary/secondary schools.

Sector Other Industries

Contact Details

Company Name UNIVERSITE DE LAUSANNE
Web Site https://cordis.europa.eu/project/rcn/214087_en.html

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