Prior Information Notice Without Call For Competition Antibacterials For Systemic UseMarket Investigation Contract Producer For Fermentation And Preparation Of AntibioticsDescription For The Further Accelerated Development Of The New Anticonvulsant And Antibiotic Corallopyronine A Companies Are Looking For Companies All Over Europe Who Are Interested In A Development Order For A Feasibility Study On The Next Larger Scale With Fermenters Up To 10 M3Total Volume Interested Companies Should Ideally Have Experience In The Fermentation Of Myxobacteria And Additionally Have A Genetic Engineering License For The Use Of Recombinant Myxobacteria In Addition A Downstream Reprocessing Plant Dsp Down Stream Processing Is Required In Which The Pre Optimized Necessary Process Steps Can Be Carried Out These Are Cell Separation With Separator Drug Adsorption On Plastic Resins Such As Xad 16 Filtration And Elution Of The Resin With Alcoholic Organic Solvents Concentration And High Purification Of Corallopyrone A By A Medium Pressure Chromatography System With Acetonitrile Concentration And Primary Crystallization In A Stable Form Using Chlorinated Solvents According To Our Specifications For Cost And Logistics Reasons It Is Necessary That Fermentation And Work Up Dsp Take Place At The Same Location Interested Companies Are Kindly Asked To Informally Inform Themselves About The O G To Contact The Contact Point Preferably By E Mail Disclaimer The Above Text Is Machine Translated For Accurate Information Kindly Refer The Original Document
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